Research Project
Bioimaging offers non-invasive analytical tools that have led to significant advances in biomedical research. Technological and methodological developments, along with those in imaging probe chemistry, particularly in the field of theranostics, have improved the sensitivity and specificity of images for early diagnosis and therapeutic purposes.
The project involves carrying out these different steps from in vitro to in vivo models in the search for biomarkers, the development of diagnostics or therapies, using MRI techniques and preclinical optical imaging. These include the design, characterization, and evaluation of new imaging probes or formulations for biomedical research on pathologies of interest (cancer, ischemia, inflammation) in preclinical settings. MRI imaging methodologies combined with optical imaging are proposed to reveal specific contrasts and perform multiparametric image treatments and analyses.
The Junior Professor will participate in the writing of national and international projects, be heavily involved in the development of technological platforms, and drive the valorization of the research produced by the team.
Teaching Project
The teaching project aims to transmit the basics of research and methodologies developed around bioimaging, a modern method increasingly widespread and favored for biomedical research in academic and industrial laboratories. It includes the description of the nature and formulation of molecular and nanoparticule imaging probes, their toxicity and therapeutic effects, physical bioimaging techniques (MRI, optics, ultrasound, PET, X-ray), classical analytical chemical and physicochemical characterization methods coupled with imaging techniques, and data and image processing and analysis. These teachings will be linked to the field of therapeutic research, particularly nanomedicine.
The teaching project format will include lectures, invitations to academic and industrial speakers, 7utorialls, and practical work in the existing master’s programs at Université PSL in Chemistry, Health Engineering, and engineering training at ENSCP. The Junior Professor will also be involved in Health Engineering training actions within the European University EELISA and in setting up courses at the Bachelor’s level at Université PSL.
The junior Professor will have a reduced teaching load during the pre-tenure period (minimum 64 hours TD per year, then a teaching load of 192 hours TD as a professor).
No additional courses or work can be undertaken during this period, which should be mainly devoted to research.
Corresponding CNU Section(s): 31, 32, 64
Keywords: bioimaging, optical and MRI spectroscopy, biomarkers, biological probes
Contract Duration: up to 6 years for the tenure-track phase, followed by tenure in the university professor corps after evaluation by a dedicated committee.
Start Date: from December 2025
Selection and Auditions
The evaluation will be carried out by a committee composed of internal and external experts to PSL. The composition of the committee will be made public before its work.
The pre-selected candidates by the committee, based on the examination of the files, will be invited to an audition in two parts:
• A practical situation: the selected candidates will have to give a public seminar, open to all members of i-CleHS and the Ecole Nationale Supérieure de Chimie de Paris, during which they will present their current research work and future research projects. They will also be invited to exchange/discuss with various laboratory contacts for the research component and with the educational managers for the teaching component. (30 minutes and 10 minutes for questions)
• An audition in person or via videoconference with the recruitment committee. This audition will be an opportunity for the candidate to demonstrate their motivation, as well as the quality, relevance, and ambition of the proposed research and teaching projects. (45 minutes)
The practical situation and the audition will be conducted in English.
Evaluation Criteria
• Excellence of the candidate, motivation, supervision capacity
• Quality, ambition, and originality of the research and teaching projects
• Integration of the project within the laboratory
• Ability to establish collaborative networks
• Adequacy of the means to the proposed project and ability to mobilize additional resources
Provisional audition period: October-November 2025
Application Procedure:
How to Apply?
Candidates must submit an application file on the Odyssée application. To do this, they must first register here (https://www.galaxie.enseignementsup-recherche.gouv.fr/ensup/cand_recrutement_enseignants_chercheurs_Odyssee.htm) and click on the “Accès Recrutement EC hors santé / Odyssée” button on the right side of the page. You will arrive at the ODYSSEE login page.
Only files entered and submitted on the Odyssée platform will be acceptable. All documents must be uploaded to this platform. No documents sent by email will be considered.
Application form:
This file consists of a form to be completed online and documents to be uploaded:
Administrative documents:
• Photo ID
• Copy of doctorate diploma or recognized equivalent
• Examination report or a certificate from the institution stating that no examination report has been drawn up
• Présentation analytique
Additional compulsory documents, to be uploaded in the “Titles and work” section:
• Application form downloadable here: https://www.galaxie.enseignementsup-recherche.gouv.fr/ensup/cand_CPJ.htm
• Cover letter
• Two letters of recommendation (also to be sent to cpj@psl.eu)
• Works, books, articles and achievements mentioned in the analytical presentation and which the candidate intends to present at the audition, up to a maximum of 6 documents.
All documents must be uploaded in PDF format and must not exceed 10MB.
Application deadline: Monday September 29, 2025, 4pm (Paris time)
Candidates must hold a doctorate and have a research record including high-impact publications in fields relevant to the job profile. Significant international experience is desirable.
The gross annual salary will be €43,714 during the pre-tenure period. This salary is slightly negotiable depending on the candidate’s initial background. In addition, the Junior Professor Chair will benefit from a support package of €200,000 over the contract duration (including the salary of a PhD student and/or a postdoctoral researcher, as well as equipment and operating expenses).
Université PSL is launching a call for applications for a Junior Professor Chair in Chemistry titled ” Bio-imaging and Probes for Diagnostic”.
The activity will take place at the Institute of Chemistry for Health and Life Sciences (i-CLeHS, ENSCP-PSL, https://www.chimieparistech.psl.eu/en/research-at-chimie-paristech/laboratories/i-clehs-en/).
This is a tenure track position with a reduced teaching load leading to a full professor position at the i-CLeHS (ENSCP-PSL).
The position will start as early as December 2025 (or at a mutually agreed later date).
The position is open to all researchers wishing to develop their activity in Chemistry at the interface with biology and medicine. The position includes an internationally competitive salary and competitive start-up package.
Wholly committed to excellence in education, training and research, PSL is a global university, which aims to reflect, represent and influence society today and the world of the future in all its diversity. The university’s collegial ethos is a major asset. Made up of eleven component institutions, including the Ecole Nationale Supérieure de Chimie de Paris, PSL ensures that dialogue takes place between all areas of knowledge, innovation and creativity in science, humanities, social sciences, arts and engineering. PSL offers an education led by the research carried out in its laboratories while encouraging discussion and mobility between disciplines and across schools. Our university exercises critical thinking and fosters creativity. Students are selected on the basis of their potential and talent. The university champions equal opportunities and promotes social, cultural and geographic diversity, and students are guaranteed individual mentoring, small class sizes and personalized academic pathways.
This recruitment is part of the development project of the Institute of Chemistry for Health and Life Sciences (iCLeHS), and more specifically the activities of the SEISAD team (Electrochemical Synthesis, Imaging, and Analytical Systems for Diagnosis). The laboratory, already highly visible internationally for its research in chemobiology (Prof. Gilles Gasser, ERC CoG), organic synthesis (Dr. Guillaume Lefèvre, ERC StG), and theoretical chemistry (Prof. Carlo Adamo, ERC AdG, and Dr. Ilaria Ciofini, ERC CoG), wishes to expand research activities related to health engineering developed within the SEISAD group.
The SEISAD team develops projects aimed at 6utoriing processes and tools for the early detection of pathological signals using chemical and analytical methodologies. The team combines expertise in (1) electrochemical biosensors, high-performance separation methods, and lab-on-a-chip design, (2) design of new nano-supports and selective objects for optical and magnetic resonance imaging agents, and (3) development of functional MRI and optical imaging methods and image processing for preclinical theranostics.
Currently, some of these themes are understaffed relative to their scope. Therefore, the recruitment in the field of bioimaging, from the chemical object to its characterization and evaluation, fits into the development strategy of the SEISAD group and the laboratory. This strategy is highly complementary to the existing medical imaging developments at ESPCI-PSL and within the team (activity of Dr. B.T. Doan), with an emphasis on the design and use of new nano-objects as imaging agents.
The recruitment of the Junior Professor in Bioimaging will strengthen PSL’s actions in Health Engineering and the European University EELISA, of which PSL is a part. This will increase the attractiveness of PSL and, more specifically, of Chimie Paris-PSL towards our European partners such as the Scuola Normale Superiore and Sant’Anna di Pisa. This will increase the volume of our student exchanges not only at the master’s level but also at the doctoral level, as well as the development of an Erasmus Mundus master’s program. This could then lead to the establishment of double degree agreements between the different schools.
