This PhD project aims at obtaining a general methodological and experimental framework for trustworthy and reproducible validation and benchmarking of deep learning methods in brain imaging and performing large-scale experiments.
Specific objectives are as follows:
– Enrich the framework with more advanced deep learning models, more tasks and more datasets
– Better account for specificities of brain imaging (multiple acquisitions over time, multiple scanners, multiple hospitals, multiple datasets, multiple disorders)
– Propose an adequate inferential statistics framework for both model validation and model comparison
– Perform benchmarking experiments across deep learning (and also standard machine learning) models, tasks, diseases and datasets to create a new standard for the community
– Demonstrate the importance of accounting for brain imaging specificities when evaluating models
– Implement the approaches in open-source software, in particular ClinicaDL so that they can benefit the entire scientific community