Coordination: Dr. Benoit Haelewyn
benoit.haelewyn@unicaen.fr
Project manager: in progress
Local administrative coordination: Université de Caen and Université de Lille
About the hub
The hub Nord Ouest is the latest France Life Imaging (FLI) hub, integrated into the infrastructure on January 1, 2025. It brings together two major IBISA-certified multimodal imaging platforms:
- LiiFE (Lille In vivo Imaging and Functional Exploration) in Lille (https://ums-plbs.univ-lille.fr/les-plateformes-constitutives/imagerie-du-vivant-exploration-fonctionnelle)
- Cyceron in Caen (https://www.cyceron.fr/index.php/fr/).
These platforms are supervised by :
- INSERM, Université de Lille, Institut Pasteur de Lille and CHU de Lille for LiiFE,
- Inserm, CNRS and the University of Caen for Cyceron.
The Lille and Caen sites offer integrated in vivo imaging modalities and experimental models for a better understanding of the physiology and pathophysiology of human diseases, including neurology, psychiatry, oncology and cardiology.
State-of-the-art equipment for preclinical and clinical research
The Hub Nord-Ouest provides a multimodal imaging park with state-of-the-art equipment:
In Lille :
Clinical research:
- 7T MRI dedicated to research (shared with the CHU (“teaching hospital”) Amiens)
- 3T MRI
- OCT Spectralis Heidelberg
Preclinical research:
- 7T µ-MRI IRM for rodents
- µ-PET-CT for rodents
- 0.2T MRI for larger animals
- A platform for functional and behavioral exploration
In Caen :
Clinical research:
- 3T MRI + EEG MRI compatible
- PET-TDM
Preclinical research:
- 7T µ-IRM
- 7T-PET µ-MRI with cryoprobe
- µ-TEP-TDM for rodents
- IRM 3T et TEP-TDM for larger animals
- MPI (Magnetic Particle Imaging) for mice (unique in France)
- HIFU for small and larger animals
- X-ray angiography
- X-ray irradiator
- Clean room for the production of radiopharmaceutical agents
Expertise in biomedical imaging
The Hub Nord-Ouest offers advanced integration of in vivo imaging modalities and experimental models to improve understanding of human physiology and pathology.
Areas of expertise:
- Development of experimental models
- Innovative multimodal imaging
- Radioisotope production and chemistry for imaging
- Expertise in cerebral, cardiac, oncological and retinal imaging
- Functional and behavioral explorations
- Image acquisition, harmonization and processing
- Artificial intelligence applied to imaging
- Scientific valorization and project support
Preclinical and clinical imaging platforms / Location / Scientific leaders :
The platforms are open to collaborations and imaging research services with academic and industrial partners.
- Plateforme LIIFE – Lille In vivo Imaging and Functional Exploration (20 persons)
Campus du CHU de Lille, UFR 3S, Pôle Recherche
Managers: Pr. Jean-Pierre Pruvo and Dr. Renaud Lopes
https://ums-plbs.univ-lille.fr/les-plateformes-constitutives/imagerie-du-vivant-exploration-fonctionnelle
- Plateforme CYCERON (50 persons)
Campus EPOPEA, in Caen
Manager : Dr. Benoit Haelewyn
https://www.cyceron.fr/index.php/fr/
Research laboratories associated to the platforms:
Lille :
- U1172 LillNCog « Lille Neuroscience & Cognition » (https://lilncog.eu/)
- UMR 1011 « Nuclear receptors, metabolic and cardiovascular diseases » (https://pasteur-lille.fr/centre-de-recherche/unites-de-recherche/recepteurs-nucleaires-maladies-metaboliques-et-cardiovasculaires/)
- U1008 « Advanced Drug Delivery Systems » (https://u1008.univ-lille.fr/)
- U1189 OncoThai « Laser assisted therapies and immunotherapies for oncology » (https://www.oncothai.fr/fr/component/tags/tag/onco-thai)
- UMR 1003 PhyCell « Laboratory of Cell Physiology » (https://phycell.univ-lille.fr/)
- UMR 9020 CNRS UMR 1277 Inserm Canther “Cancer Heterogeneity Plasticity and Resistance to Therapies” (https://canther.fr/en/canther-cancer-heterogeneity-plasticity-and-resistance-to-therapies/)
- UMR 1190 RTD « Transnational Research for Laboratory for Diabetes » (https://www.translational-research-diabetes.com/FR/index)
- UMR 1283 / 8199 « Functional (Epi)genomics and Mechanisms of Type 2 Diabetes and Related Diseases » (https://www.good.cnrs.fr/)
- U1286 INFINITE « Institute for Translational Research in Inflammation » (https://lille-inflammation-research.org/fr/)
- Inserm U1019 -CNRS UMR9017 CIIL « The Center for infection and immunity » (https://www.ciil.fr/fr/)
- ULR 4483 – IMPECS « Impact de l’environnement chimique sur la santé » (https://impecs.univ-lille.fr/)
Caen :
- UMR 1237 PhIND « Physiopathology and Imaging of Neurological Disorders » (https://www.phind.fr/index.php/en/)
- UMR 1077 NIMH – BB@C « Neuropsychologie et Imagerie de la Mémoire Humaine » (https://nimh.unicaen.fr/fr/accueil/)
- UMR 1075 COMETE « Mobilités : Vieillissement, Pathologies, santé » (https://comete.unicaen.fr/)
- UMR 6030 ISTCT « Imagerie & Stratégies Thérapeutiques pour les Cancers & Tissus Cérébraux » (https://www.istct.cyceron.fr/index.php/fr/)
- UMR 8240 LaPsyDÉ « Labortory for the Psychology of Child Development and Education » (https://www.lapsyde.com/)
- UR 4650 PSIR « Physiopathologie et Stratégie d’Imagerie du Remodelage cardiovasculaire » (https://www.unicaen.fr/laboratoire/ur-4650-physiopathologie-et-strategies-dimagerie-du-remodelage-cardiovasculaire-psir/)