2019/10/18 – Research Engineer Position (2 years)
Background and mission :
In the frame of the MULTIMOD program supported by the Regional Council and the European Union, ICMUB is seeking a highly motivated candidate with strong chemistry and bioconjugation background to design, prepare and characterize protein or peptide-based conjugates for imaging/therapy purposes. The selected candidate will have the opportunity to closely interact with the local imaging cluster and the preclinical imaging platform members. He/she will contribute to the team’s mission of delivering in time, fully defined conjugates to our academic/industrial partners.
The successful candidate will have the following responsibilities:
– Involvement in various R&D and public/private programs
– Synthesis of bioconjugates, by modification of home-made proteins/peptides or coming from our partners
– Development and implementation of robust analytical methods to fully characterize antibody-based conjugates
– Synthesis of specific molecular probes, in collaboration with researchers involved in technology transfer programs
– Preparation of technical documents, summary reports and regular updates on project status
– Participation to valorization actions.
Starting date: Asap
Diplomas required :
PhD degree
Skills required:
Proven track record in organic chemistry and protein labelling – Strong experience with chromatography and mass spectrometry data analysis and method development – Ability to execute technical tasks independently to achieve projects goals on an established timeline and to work in a collaborative environment – Highly organized and able to manage multiple tasks – Excellent written and oral communication skills, adaptability. Preferred but not required: – Experience in radiochemistry and molecular imaging
Structure :
The Institut de Chimie Moléculaire de l’Université de Bourgogne (ICMUB), in Dijon is involved in the development of innovating tools for medical imaging techniques such as nuclear imaging (PET/SPECT) or fluorescence imaging. The group is specialized in the design of new imaging probes, such as chelators (i.e. DOTA-like compounds), fluorophores, as well as their immobilization on biological vectors (peptides, antibodies, …) through innovative bioconjugation chemistry.